Capsule-based DPIs – Understanding the science
Drug delivery via the pulmonary route is well established for the treatment of localised diseases such as asthma and COPD, though it has attracted attention recently as a portal for systemic diseases as well. A number of devices exist in the market to facilitate inhaled drug delivery, each with its particular advantages and disadvantages. One such type of device is a dry powder inhaler (DPI).
Some DPIs operate with hard shell capsules as single unit drug reservoirs that are punctured in situ prior to aerosolisation. Many capsule formulations have been used in DPIs, and as these may behave differently, it is important to understand which key capsule characteristics determine their suitability.
This webinar will discuss several capsule formulations used in DPIs and will compare their performance. It will provide an overview on some of the novel methods being employed to evaluate the physical characteristics and mechanical properties of capsules, and will also address the factors influencing the aerosolisation performance of different capsule types.
Key learning objectives:
- Key advantages of DPIs and considerations when choosing a hard capsule
- Overview on some of the novel methods being employed to evaluate the physical characteristics and mechanical properties of capsules
- Key factors influencing the aerosolization and aerodynamic performance of different capsule types
Our webinar is free and open to anyone who wants a better understanding of the relevant aspects when undertaking a new drug development cost/benefit analysis, as well as the versatility and positive appreciation of the capsule solid oral dosage form.
To view the webinar in on demand mode, click on the link below to register